POLARIS

Multi-Modality Guidance System

Pd/Pa = iFR, like °C = °F

“Pd/Pa seems to offer a universal resting physiological metric with equivalent agreement to iFR. Although not numerically identical, 1 index can be linearly transformed into the other, much like the conversion of units of temperature. Using the binary cutoff of iFR ≤0.89 as a reference standard, Pd/Pa showed excellent agreement according to ROC curve analysis and the best cutoff value of Pd/Pa was ≤0.91.”

-Kobayashi Y, et al. JACC Oct 2017.

 

 

Pd/Pa

iFR

Single Cutoff1

≤0.91

≤0.89

Hybrid Algorithm2,3

0.88-0.97

0.86-0.93

FDA-Cleared4

?

?

Inclusion in Appropriate Use Criteria5,6

?

?

SCAI/ACC Reimbursement Recommendation7

?

?

Equivalent Correlation to FFR8,9,10,11

?

?

Equivalent Correlation to CFR12

?

?

Results Integrate into All Major Hemodynamic Systems

?

X

ECG-free Algorithm Widely Available13

?

X

Workhorse Pressure Guidewire Available

?

X

Pd/Pa and iFR contain 95% of the same information11

 

Pd/Pa and iFR Compared to Other Physiologic Indices

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